N-Isovaleroylglycine 是酰基甘氨酸,能够作为体重提高和肥胖的生物标记物。
产品描述
Isovalerylglycine (IVG) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases, the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine< -- >CoA + N-acylglycine. Isovalerylglycine is a byproduct of the catabolism of the amino acid leucine. Accumulation of isovalerylglycine occurs in Isovaleric Acidemia (IVA).
Cas No.
16284-60-9
分子式
C7H13NO3
分子量
159.18
别名
Isovaleroylglycine;N-Isovalerylglycine;N-异戊酰氨基乙酸;N-Isovaleroylglycine
储存和溶解度
DMSO:5 mg/mL
Methanol:2 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years