OSMI-3 is a potent, long-lasting and cell-permeable inhibitor of O-linked N-acetylglucosamine transferase (OGT).

OSMI-3 ( HCT116 cells) treatment significantly reduces O-GlcNAc levels, and has more sustained cellular effects than OSMI-2[1].?A decrease in HCF-1 cleavage products and the appearance of uncleaved HCF-1 in cells treated with OSMI-3 (Compound 2b) is observed.

2260791-13-5

C32H35N3O9S2

669.77

OSMI-3

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years