AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively[1]. AZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats.

AZD2906 is a selective glucocorticoid receptor (GR), with IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively[1].

AZD2906 (5, 25, 50 mg/kg, p.o.) increases micronucleated immature erythrocytes (MIE) in the bone marrow of rats after treatment for 2 days[1]. AZD2906 (5, 25 mg/kg, p.o.) induces an accumulation of glycogen in the liver of rats. And it exhibits cortical lymphocytic atrophy of a moderate to marked degree in the thymus of rats[1].

1034148-15-6

C26H25FN4O3

460.5

AZD2906

DMSO:125 mg/mL (271.44 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years