Aurora A/PKC-IN-1 (Compound 2e) 是一种有效的Aurora A (AurA)和PKC (α, β1, β2, θ)双效抑制剂，对 AurA 和 PKCα 分别具有 6.9 nM 和 16.9 nM。Aurora A/PKC-IN-1对乳腺癌细胞具有抗增殖和抗转移活性。

Aurora A/PKC-IN-1 (Compound 2e) is a potent dual inhibitor of Aurora A (AurA) and PKC (α, β1, β2, and θ) kinases with IC 50 s of 6.9 nM and 16.9 nM for AurA and PKCα, respectively. Aurora A/PKC-IN-1 has antiproliferative activity in breast cancer cells and antimetastatic activity [1].

2143100-98-3

C16H14N6OSe2

464.24

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years