PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.

PF-06726304 inhibits the proliferation of Karpas-422 cells that harbor wild-type EZH2 (IC50 of 25 nM)[1].

In a subcutaneous Karpas-422 xenograft model,PF-06726304 inhibits tumor growth and induces robust modulation of downstream biomarkers [1].

2080306-28-9

C24H25Cl2N3O5

506.38

PF-06726304 acetate

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years