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Bobcat339 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2436747-44-1
包装与价格:
包装价格(元)
100 mg电议
200 mg电议

产品介绍
BobCAT339 hydrochloride 是一种有效的、选择性的基于胞嘧啶的TET酶抑制剂,抑制TET1和TET2的IC50值分别为 33 μM 和 73 μM。BobCAT339 hydrochloride 可用于表观遗传学领域研究,并且可作为靶向 DNA 甲基化和基因转录新疗法的起点。

产品描述

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme, with the IC 50 s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription [1].

体外活性

Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells [1].

Cas No.

2436747-44-1

分子式

C16H13Cl2N3O

分子量

334.2

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years