Collagen-IN-1 (compound 3) 是一种邻羰基对苯二酚衍生物，是一种选择性的胶原蛋白 (collagen) 抑制剂。Collagen-IN-1 以非竞争性方式抑制激动剂诱导的血小板聚集，其IC50值为 1.77 μM。Collagen-IN-1 降低 P-selectin 的表达、糖蛋白 IIb/IIIa 的激活、以及三磷酸腺苷和 CD63 从血小板的释放。Collagen-IN-1 在血小板相关血栓形成疾病的研究中具有潜力。

Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative that is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC 50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research [1].

104260-73-3

C14H14O3

230.26

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years