| CAS NO: | 61-12-1 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 500mg | 电议 |
| 1g | 电议 |
| 2g | 电议 |
| 5g | 电议 |
| 10g | 电议 |
| 100g | 电议 |
| Molecular Weight (MW) | 379.92 |
|---|---|
| Formula | C20H29N3O2.HCl |
| CAS No. | 61-12-1 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 76 mg/mL (200.0 mM) |
| Water: 76 mg/mL (200.0 mM) | |
| Ethanol: 76 mg/mL (200.0 mM) | |
| Other info | Chemical Name:
2-Butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide hydrochloride InChi Key: IVHBBMHQKZBJEU-UHFFFAOYSA-N InChi Code: InChI=1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H SMILES Code: O=C(C1=CC(OCCCC)=NC2=CC=CC=C12)NCCN(CC)CC.[H]Cl |
| Synonyms | Cinchocaine hydrochloride; Cincaine chloride; Cinchocaine HCl; Dibucaine HCl; Cincain; Nupercainal; Nupercaine; Sovcaine |
| In Vitro | In vitro activity: Dibucaine (Cinchocaine) HCl is one of the most potent and toxic of the long-acting local anesthetics. Dibucaine (Cinchocaine) HCl blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade. |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Biochim Biophys Acta. 1987 May 29;899(2):196-204; Biochim Biophys Acta. 1987 May 29;899(2):196-204. |
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