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Steroid sulfatase-IN-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
5 mg电议
50 mg电议
100 mg电议

产品介绍
Steroid sulfatase-IN-4 (Compound 16) 是一种不可逆的类固醇硫酸酯酶 (STS) 抑制剂,对人 STS 的IC50为 25 nM,可用于子宫内膜异位的研究。

产品描述

Steroid sulfatase-IN-4 (Compound 16) is an irreversible steroid sulfatase ( STS ) inhibitor with an IC 50 of 25 nM against human STS. Steroid sulfatase-IN-4 can be used for the research of endometriosis [1].

体外活性

Steroid sulfatase-IN-4 (Compound 16) shows good metabolic stability in human hepatic S9 fraction and low intrinsic clearance Clint (<30 μL/min/mg protein) [1]. Steroid sulfatase-IN-4 (20 μM; 24 h) shows cytotoxicity for HEK-293 cells (53.6% inhibition) [1]. Steroid sulfatase-IN-4 (1 μM) shows 25% inhibition against human 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) in a cell-free assay [1].

分子式

C19H17ClN2O5S

分子量

420.87

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years