(R)-Pirtobrutinib ((R)-LOXO-305) is a less active enantiomer of Pirtobrutinib. Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations[1].

2101700-14-3

C22H21F4N5O3

479.436

(R)-Pirtobrutinib

DMSO:200 mg/mL (417.16 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years