EGFR-IN-55 (Compound 8a) 是一种有效的EGFR抑制剂，对EGFRWT和EGFRL858R/T790M的IC50值分别为 70 nM 和 3.9 nM。EGFR-IN-55 阻滞 NCI-H1975 细胞 G0/G1 期，具有抗癌活性。

EGFR-IN-55 (Compound 8a) is a potent EGFR inhibitor with IC 50 values of 70 nM and 3.9 nM against EGFR WT and EGFR L858R/T790M, respectively. EGFR-IN-55 arrests NCI-H1975 cells in G0/G1 phase and shows anticancer activity [1].

2057423-46-6

C25H25Cl2N7O2

526.42

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years