CCG-273463 是一种有效的、共价的GRK5选择性抑制剂，IC50值为 9 nM。CCG-273463 可用于心力衰竭、肥厚型心肌病和癌症的研究。

CCG-273463 is a potent, selective and covalent GRK5 inhibitor with an IC 50 value of 9 nM. CCG-273463 can be used in the research of heart failure, hypertrophic cardiomyopathy, and cancer [1].

CCG-273463 (0.02-1 μM) potently and highly inhibits GRK5 (IC 50 : 9 nM), with inhibitory rate of 93% (GRK5) and 97% (GRK6) at 1 μM [1].

2750413-99-9

C26H25BrN4O3

521.41

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years