PSB-1114 tetrasodium shows >50-fold selectivity versus the P2Y4 (EC50: 9.3 μM) and P2Y6 (EC50: 7.0 μM) receptors. PSB-1114 tetrasodium is an effective, enzymatically stable, and subtype-selective P2Y2 receptor agonist (EC50: 134 nM) .

PSB-1114 may be a useful pharmacological tool for studying P2Y2 receptors. PSB-1114 (4-Thio-β,γ-difluoromethylene-UTP) shows >60-fold selectivity versus P2Y4 and P2Y6 receptors. Because of its high potency, selectivity, and expected metabolic stability toward ectonucleotidases, in particular NTPDases [1].

1657025-60-9

C10H15F2N2Na4O13P3S

626.17

PSB-1114 tetrasodium

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years