FXa-IN-1 是一种FXa抑制剂 (IC50: 3 nM,Ki: 0.7 nM)，具有可观的口服生物利用度和半衰期 (in vivo)。FXa-IN-1 可用于血栓栓塞性疾病的研究。

FXa-IN-1 is a FXa inhibitor ( IC 50 : 3 nM, K i : 0.7 nM) with respectable oral bioavailability and half-life in vivo. FXa-IN-1 can be used for thromboembolic disorders [1].

FXa-IN-1 (compound 22, rats) exhibits good oral bioavailability (F%: 46.9) and half-life (t 1/2 : 8.8 h, i.v.) [1].

441328-10-5

C24H18F5N5O

487.42

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years