MitoBloCK-10 是第一个能够减弱PAM复合体活性的小分子调节剂，对 C 末端结构域的Tim44与前体和 HSP70 结合具有抑制作用。

MitoBloCK-10 inhibits Tim44 binding to the precursor and to Hsp70.MitoBloCK-10 is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity.

394694-98-5

C12H8FN3O3S

293.27

3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m;MitoBloCK-10

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years