5-Benzyloxygramine 是一种 N 蛋白、蛋白互作的原位稳定剂,具有抗病毒和稳定 N-NTD 蛋白的作用。它能够阻断多巴胺受体,可拮抗 5-HT 对大鼠子宫和兔耳的作用。
产品描述
5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.
体外活性
5-Benzyloxygramine is a new N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic interactions with both partners, resulting in abnormal N protein oligomerization that was further confirmed in the cell[1].
Cas No.
1453-97-0
分子式
C18H20N2O
分子量
280.36
别名
5-Benzyloxygramine
储存和溶解度
DMSO:250 mg/mL (891.71 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years