Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. The 8(S),9(R)-EET isomer is metabolized by platelet COX to form 8(S),9(R),11(R)-THETA, a trihydroxy fatty acid which may act as a renal vasoconstrictor.

192461-96-4

C20H34O4

338.48

(±)8(9)-DiHET

DMSO:50 mg/mL
DMF:50 mg/mL
Ethanol:50 mg/mL
PBS (pH 7.2):1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years