Medetomidine(Domtor)是一种有效的、高选择性的、具有口服活性的α2肾上腺素受体激动剂，对α2和α1肾上腺素受体的Ki值分别为1.08 nM和1750 nM。

Medetomidine(Domtor) is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). IC50 value: Target: α2-adrenoceptor Medetomidine displays greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Medetomidine inhibits twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0). Medetomidine is active in vivo and displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects.

86347-14-0

C13H16N2

200.28

Medetomidine

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years