(+)-Penbutolol is an antagonist of β-adrenoceptor(IC50 of 0.74 μM). (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.

LPC is concentration-dependent induce (+)-penbutolol on the [Ca2+]i-increase [1]. (+)-penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10-6 M, 5×10-6 M and 10-5 M, respectively)[2].

38363-41-6

C18H29NO2

291.43

(+)-Isopenbutolol;(R)-Penbutolol;(+)-Penbutolol

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years