GR 125743 是选择性的5-HT1B/1D受体拮抗剂，与野生型的人 h5-HT1B和 5-HT1D结合的pKi分别为 8.85 和 8.31，可用于帕金森病和心血管疾病的研究。

GR 125743 is a novel antagonist of 5-HT1B/1D receptor.

GR-125743, a new radiolabelled derivative of a compound that exhibits selective antagonistic properties with respect to the serotonin human (h5-HT1D) and human (h5-HT1B) receptors.?The compound has been characterized for its ability to label the cloned h5-HT1D and h5-HT1B receptors.

148547-33-5

C25H28N4O2

416.525

GR 125743

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years