ML 297 是选择性的GIRK1/2激活剂，EC50为 0.16 μM。ML 297 在癫痫病的研究中具有价值。

ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.

1443246-62-5

C17H14F2N4O

328.11

ML297;ML 297

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years