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RO27-3225 TFA(274682-89-2 free base)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
100 mg电议
500 mg电议

产品名称
RO27-3225 TFA
RO27-3225 TFA (274682-89-2 free base)
产品介绍

产品描述

RO27-3225 TFA is a potent and selective agonist of melanocortin 4 receptor (MC4R; EC50: 1 nM and 8 nM for MC4R and MC1R) with neuroprotective and anti-inflammatory effects. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R.

体内活性

RO27-3225 could have a protective role against multiple organ failure following the circulatory shock. RO27-3225 (0.012-0.048 mg/kg; i.v.; Wistar rats) treatment reverses haemorrhagic shock, reduces multiple organ damage and improves survival [2].

Cas No.

TP2154

分子式

C41H53F3N12O8

分子量

898.93

别名

RO27-3225 TFA;RO27-3225 TFA (274682-89-2 free base)

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years