Dehydroepiandrosterone sulfate 影响神经元的迁移、树突的分枝和新突触的形成。
产品描述
Dehydroepiandrosterone sulfate influences the migration of neurons, arborization of dendrites, and formation of new synapses.
体外活性
Dehydroepiandrosterone sulfate selectively increases the length of neurites containing the dendritic marker MAP-2 and increases neuronal excitability when directly applied to septal-preoptic neurons[1].
体内活性
Chronic administration of Dehydroepiandrosterone sulfate produces a dose-dependent effect on performance. In male Sprague-Dawley rats, Dehydroepiandrosterone sulfate (5-20 mg/kg; s.c.) is significantly effective in improving latency to reach the platform[3].
Cas No.
651-48-9
分子式
C19H28O5S
分子量
368.49
别名
DHEAS;PB005;PB-005;Prasterone sulfate;PB 005;DHEA sulfate;Dehydroepiandrosterone sulfate
储存和溶解度
DMSO:91.8mg/mL (249.1mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years