D-glutamic acid 是一种广泛用于药物和食品中的L-glutamic acid对映异构体。

D-glutamic acid, the enantiomer of L-glutamic acid, is widely used in medicine and food.

Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp) and D-glutamic acid (D-Glu) are widely found in mammals including humans and are now considered to be their Candidate. New physiologically active substances and / or biomarkers. D- [Asp / Glu] (4 mg / mL) inhibited the binding of IgE to peanuts (75%), while D-Glu and D-Asp had no inhibitory effect. IgE is specific to D- [Asp / Glu] and may have the potential to remove IgE or reduce the binding of IgE to peanut allergens.

At present, D-glutamic acid is receiving attention as a regulator of neuronal transmission and hormone secretion. It is only metabolized by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamic acid is catabolized by α-ketoglutarate, and D-glutamic acid is converted to n-pyrrolidone carboxylic acid. The carbon 2 of D- and L-glutamic acid is converted to methyl acetate in the cecum. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.

6893-26-1

C5H9NO4

147.13

D-谷氨酸;(R)-Glutamic acid;D-Glutamic acid

H2O:10 mg/mL (67.97 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years