BACE-1 inhibitor 2 是一种有效的，可透过血脑屏障的BACE-1抑制剂，IC50为 1.5 nM。

BACE-1 inhibitor 2 is a potent and CNS permeable BACE-1 inhibitor with an IC 50 of 1.5 nM in BACE-1 enzymatic assay [1].

BACE-1 inhibitor 2 inhibits Aβ42 production in human neuroblastoma cell lines with an IC 50 of 3.5 nM [1].

C21H21F4N5O3

467.42

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years