TRK-IN-17 是一种有效的TRK抑制剂。原肌球蛋白相关激酶 (Trks) 是由神经营养因子激活的受体酪氨酸激酶家族，神经营养因子是一组可溶性生长因子，包括神经生长因子 (NGF)、脑源性神经营养因子 (BDNF) 和神经营养因子-3 (NT-3)，以及神经营养因子-4/5 (NT-4/5)。TRK-IN-17具有研究癌症疾病的潜力（摘自专利 WO2021148807A1，化合物 3）。

TRK-IN-17 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-17 has the potential for the research of cancer diseases (extracted from patent WO2021148807A1, compound 3) [1].

2409544-80-3

C21H21F2N7S

441.5

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years