PQ-10 是磷酸二酯酶 10A 抑制剂，其IC50=4.6 nM，ED50=13 mg/kg。它能够诱导大脑葡萄糖代谢模式，这可能是潜在的转化生物标志物。它对精神分裂症等精神疾病具有研究潜力。

PQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.

In mice, PQ-10 shows a region-specific increase in 2-DG uptake in the globus pallidus (equivalent to the outer part of the primate pallidus) and lateral habenula [1].

927691-21-2

C22H21N5O3

403.44

A-844337;A 844337;A844337;PQ 10;PQ-10

DMSO:60 mg/ml (148.72 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years