Metapramine (19560 RP) 是一种三环类抗抑郁剂。Metapramine 抑制去甲肾上腺素 (Norepinephrine) 的再摄取，而不影响血清素或多巴胺的再摄取。Metapramine 是N-methyl-D-aspartic acid (NMDA) 受体复合物通道的低亲和力拮抗剂。

Metapramine (19560 RP) is a tricyclic antidepressant[1]. Metapramine inhibits norepinephrine reuptake without affecting the reuptake of serotonin or dopamine [1] [2] [3]. Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid ( NMDA ) receptor complex channel [4].

Metapramine (19560 RP) (0-20 mg/kg; i.p.) has analgesic effect in mice [5]. Animal Model: Male Swiss albino mice [5] Dosage: 0-20 mg/kg Administration: Intraperitoneal injection Result: Increased jump latency, threshold voltage, reduction in writhes, and tail flick latency in a dose-dependent manner.

21730-16-5

C16H18N2

238.33

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years