Myceliothermophin E is a polyketide-amino acid hybrid fungal metabolite that has been found inT. thermophilusand has anticancer and antimicrobial activities.1,2It is cytotoxic to DLD-1, Hep3B, HepG2, and HGC-27 cancer cells (IC50s = 0.32, 0.42, 0.26, and 0.08 μg/ml, respectively).1Myceliothermophin E is active against methicillin-resistant, but not -sensitive,S. aureus(MICs = 15.8 and >100 μM, respectively).2

955083-90-6

C26H37NO2

395.58

Myceliothermophin E

DMF:Soluble
Methanol:Soluble
Ethanol:Soluble
DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years