6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3

5396-25-8

C13H11Cl2N

252.14

6,9-Dichloro-1,2,3,4-tetrahydroacridine

Ethanol:1 mg/mL
DMSO:1 mg/mL
DMF:5 mg/mL
DMF:PBS (pH 7.2) (1:2):0.33 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years