NAMPT-IN-9 (Compound 8) 是一种有效的、具有抗癌活性的NAMPT抑制剂。NAMPT-IN-9 可用于胰腺导管腺癌的研究。
产品描述
Nampt-IN-9 (Compound 8) is a potent NAMPT inhibitor with anticancer activities. Nampt-IN-9 can be used for pancreatic ductal adenocarcinoma research [1].
体外活性
Nampt-IN-9 (Compound 8) shows anti-proliferative activity with IC 50 values of 0.8, 0.5, 0.004 and 0.6 nM against Jurkat, MIA PaCa-2, BxPC-3, PANC-1 cells, respectively [1]. Nampt-IN-9 (0-1 μM) blunts NAD + and ATP levels and activates caspase 3 in Jurkat leukemia cells [1].
Cas No.
2180973-35-5
分子式
C26H33N3O4
分子量
451.56
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years