Orexin receptor antagonist 4 是一种有效的选择性食欲素 2 受体 (OX2R) 拮抗剂，IC50为 4.27 nM。Orexin receptor antagonist 4 对 OX2R 的选择性是对 OX1R 的 61 倍 (IC50为 295 nM) (WO2018206959A1; example 1)。

Orexin receptor antagonist 4 is potent and selective orexin 2 receptor (OX2R) antagonist with an IC 50 of 4.27 nM. Orexin receptor antagonist 4 is 61-fold selective for the OX2R over the OX1R (IC 50 of 295 nM) (WO2018206959A1; example 1) [1].

2251017-69-1

C23H25FN4O2

408.47

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years