Mitiglinide calcium dihydrate是一种 ATP 敏感的 K+通道 (KATPchannel) 拮抗剂， 属于促胰岛素化合物。它对 Kir6.2/SUR1 复合物 (胰腺-细胞 KATP通道) 具有高度特异性，在 2 型糖尿病中有研究价值。

Mitiglinide calcium dihydrate is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide belongs to the meglitinide class of blood glucose-lowering drugs and is currently co-marketed in Japan by Kissei and Takeda.

207844-01-7

C38H52CaN2O8

704.918

S-21403 calcium hydrate;KAD-1229 calcium hydrate;米格列奈钙;Mitiglinide calcium;Mitiglinide calcium hydrate

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years