Didesmethylrocaglamide, a derivative of Rocaglamide, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. Didesmethylrocaglamide has potent growth-inhibitory activity with an IC50 of 5 nM. Didesmethylrocaglamide suppresses multiple growth-promoting signaling pathways and induces apoptosis in tumor cells. Antitumor activity[1].

177262-30-5

C27H27NO7

477.51

Didesmethylrocaglamide

DMSO:100 mg/mL (209.42 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years