RET-IN-14 (compound 49) 是一种有效的RET抑制剂，对 RET (WT)、RET (G810R)、RET (V804M)、BTK 和 BTK (C481S) 的IC50分别为<0.51 nM、9.3 nM、1.3 nM、9.2 nM 和 15 nM。RET-IN-14 具有用于肿瘤研究的潜力。

RET-IN-14 (compound 49) is a potent RET inhibitor with IC 50 s of<0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research [1]

2755843-62-8

C24H23FN8O4

506.49

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years