Ramosetron是一种血清素 5-HT3 受体拮抗剂,用于治疗恶心和呕吐。它被认为比其他第一代 5-HT3 拮抗剂如昂丹司琼具有更高的效力和更长的止吐作用。它还适用于治疗“男性以腹泻为主的肠易激综合征”。它仅获准在日本和选定的东南亚国家使用。
产品描述
Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron. Ramosetron is also indicated for a treatment of "diarrhea-predominant irritable bowel syndrome in males". It is only licensed for use in Japan and selected Southeast Asian countries.
Cas No.
132036-88-5
分子式
C17H17N3O
分子量
279.34
别名
Ramosetron
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years