(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC 50 s of >9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2).

2382768-55-8

C93H134N10O24

1776.141

(32-Carbonyl)-RMC-5552

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years