PEG3-O-CH2COOH 是一种属于 PEG 类的 PROTAC linker,可用于 SNIPER 分子的合成。
产品描述
PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based PROTAC linker. PEG3-O-CH2COOH can be used in the synthesis of SNIPERs.
体外活性
PEG3-O-CH2COOH (Compound 15b) is a PROTAC linker that can be used in the synthesis of a series of SNIPER(ER)s. SNIPERs recruit inhibitors of the apoptosis protein (IAP) ubiquitin ligases to specifically degrade targeted proteins[1].
Cas No.
51951-05-4
分子式
C8H16O6
分子量
208.21
别名
PROTAC Linker 8;三聚乙二醇-乙酸;PEG3-O-CH2COOH
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years