Apostatin-1 是一种新型 TRADD 抑制剂。 Apostatin-1 可以与 TRADD 的 N 末端 TRAF2 结合域上的口袋结合。

Apostatin-1 is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.

Apostatin-1 inhibited bortezomib induced apoptosis and ripk1 dependent apoptosis (RDA) with the IC50 of ~1μM.

2559703-06-7

C19H27N3OS

345.5

Apt-1;Apostatin-1

DMSO:65mg/ml(188.13mM),Need ultrasonic
Ethanol:9mg/ml(26.06mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years