Vesnarinone是一种喹啉酮衍生物，可抑制磷酸二酯酶III 活性，增加钙通量和减小钾通量。

Vesnarinone (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.

81840-15-5

C22H25N3O4

395.459

OPC-8212;Arkin;Piteranometozine;维司力农;Vesnarinone

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years