DNA gyrase-IN-5 (Compound 8I-w) 是一种有效的DNA gyrase抑制剂,IC50值为 0.10 μM。DNA gyrase-IN-5 对野生型和耐药株均有抗细菌(Antibacterial)活性。
产品描述
DNA Gyrase-IN-5 (Compound 8I-w) is a potent DNA gyrase inhibitor with an IC 50 of 0.10 μM. DNA Gyrase-IN-5 shows antibacterial activities against wild type and drug-resistant strains [1].
体外活性
DNA Gyrase-IN-5 (Compound 8I-w) shows antibacterial activities with IC 50 values of 4.7, 7.0, 17.0, 13.5, 1.0, 25.3 and 47.8 μM against E. coli, E. coli E564, E. coli E68, E. coli E48, E. coli E109, Salmonella and S. aureus, respectively [1].
Cas No.
2417016-23-8
分子式
C25H15BrClN5
分子量
500.78
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years