Clausine E 是脂肪量和肥胖相关蛋白 (FTO) 脱甲基酶活性的抑制剂。 Clausine E 与 FTO 的结合是由正熵和负焓变化驱动的。

Clausine E is an inhibitor of fat mass and obesity-associated protein (FTO) demethylase activity. The binding of Clausine E to FTO was driven by positive entropy and negative enthalpy changes.

182261-83-2

C14H11NO3

241.246

Clausine E

DMSO:55 mg/ml (227.99 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years