IT603 是一种c-Rel抑制剂，其IC50=3 μM。它是 E-IT-603 和 Z-IT-603的混合物。它具有抗癌作用。它有望作为调节剂调节移植物抗宿主病和恶性病中的 T 细胞反应。

IT-603 is a cell-permeable c-Rel inhibitor (IC50: 3μM). IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding and transcriptional activity.

292168-90-2

C11H9BrN2O3S

329.17

IT603;(E/Z)-IT-603

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years