BIO-11006 acetate salt (901117-03-1 free base) 是一种多糖基化富含丙氨酸的 C 激酶底物 (MARCKS) 抑制剂,类似于 MANS 肽。
产品描述
BIO-11006 acetate salt is a polyglycosylated alanine rich C kinase substrate (MARCKS) inhibitor similar to MANS peptides.
体内活性
Inhaled, aerosolized BIO-11006 attenuates LPS-induced neutrophil influx into the lung, activation of NF-κB, and expression of the proinflammatory cytokines, KC and TNF-α, and thus reverses the development of lung injury in mice instilled intratracheally with LPS[1].
Cas No.
TP1457
分子式
C48H79N13O17
分子量
1110.22
别名
BIO-11006 acetate salt;BIO-11006 acetate salt (901117-03-1 free base)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years