Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

252642-12-9

C184H297N69O43S

4195.87

Apelin-36 (human);Apelin-36(human)

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years