Anguinomycin A is an antibiotic first isolated from a Streptomyces sp. and analog of leptomycin B that is highly cytotoxic to mouse P388 leukemia cells in vitro (IC50 = 0.1-0.2 ng/ml). It also demonstrates antitumor activity at 62.5 μg/kg/day against Lewis lung carcinoma in mice.

111278-01-4

C31H44O6

512.68

Anguinomycin A

Ethanol:Soluble
Methanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years