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5(S),12(S)-DiHETE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5(S),12(S)-DiHETE图片
CAS NO:79056-01-2
包装与价格:
包装价格(元)
25 μg电议
50 μg电议
100 μg电议
1 mg电议

产品介绍

产品描述

5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12(S)-HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5(S),12(S)-DiHETE is an epimer of leukotriene B4 that is weakly chemotactic for PMNL.

Cas No.

79056-01-2

分子式

C20H32O4

分子量

336.47

别名

5(S),12(S)-DiHETE

储存和溶解度

PBS (pH 7.2):>1 mg/mL (from 13(S)-HODE)
DMF:>50 mg/mL (per Rao Maddipati)
DMSO:>50 mg/mL (per Rao Maddipati)
Ethanol:>50 mg/mL (per Rao Maddipati)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years