FEN1-IN-1 是一种FEN1的抑制剂,可绑定 FEN1 的活性位点,也可通过协调 Mg2+,进而表现出部分抑制作用。
产品描述
FEN1-IN-1 is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions.
体外活性
FEN1-IN-1 has a mean GI50 of 15.5 μM, which were obtained from 212 cell-lines[1].
Cas No.
824983-91-7
分子式
C15H12N2O5S
分子量
332.33
别名
LNT-1;FEN1-IN-1
储存和溶解度
DMSO:250 mg/mL (752.26 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years