(Rac)-Idroxioleic acid 是一种具有抗肿瘤作用的脂肪酸酰胺水解酶抑制剂。 它与质膜结合并改变脂质组织。

Minerval is a fatty acid amide hydrolase inhibitor with anti-tumor effect. It binds to the plasma membrane and alters lipid organization.

Minerval (25-50 μM; 72 hours) causes a marked and concentration-dependent increase in the proteolytic cleavage of PARP, a molecular marker of apoptosis. Minerval (25-75 μM; 72 hours) impairs Jurkat cell growth in a time- and concentration-dependent manner (IC50: 40 μM)[1].

In nude mice infected with Jurkat cells, Minerval significantly inhibits tumour growth[1].

56472-29-8

C18H34O3

298.46

2-羟基乳清酸;Minerval;2-Hydroxyoleic acid;2-OHOA;(Rac)-Idroxioleic acid

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years