EG1 是特异性Pax2<.b>抑制剂，能够直接结合 Pax2 的配对结构域 (Kd:1.35-1.5 μM) ，可阻碍 Pax2-DNA 相互作用。它能够抑制胚胎肾脏发育，此过程直接依赖于Pax2活性。

EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.

693241-54-2

C22H18N2O5

390.39

EG1

DMSO:70mg/ml(179.31mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years